Risk factors and predictive value of microvascular obstruction in patients with ST-segment elevation my-ocardial infarction after primary percutaneous coronary intervention
Li Xiaoran
Tan Jian
Wang Jiali
Abstract：Objective To discuss the risk factors for microvascular obstruction(MVO)in patients with ST-segment elevation myocardial infarction(STEMI)after primary percutaneous coronary intervention(pPCI).Methods STEMI patients undergone pPCI(n=149)were chosen from Department of Cardiology in Beijing Friendship Hospital from Oct.2019 to June 2021.The patients were received examination of cardiac magnetic resonance(CMR)within 1 week after pPCI,and divided into MVO group(n=77)and non-MVO group(n=72)according to MVO occurrence status.The general data and results of laboratory tests,including myocardial infarction location,cardiac troponin T(cTnT),N-terminal pro-brain natriuretic peptide(NT-proBNP),high sensitivity C-reactive protein(hs-CRP),urea,creatinine(Cr),thyroid stimulating hormone(TSH),low-density lipoprotein-cholesterol(LDL-C)and glycated hemoglobin(HbAlc)were compared between 2 groups.The risk factors for MVO occurrence were analyzed by using multi-factor Logistic regression analysis.Results The peak value of cTnT and hs-CRP level were higher in MVO group than those in non-MVO group(P＜0.05).The results of ROC curve analysis showed that AUC of cTnT was 0.794 and AUC of hs-CRP was 0.674 in predicting MVO in STEM patients(P＜0.05).Conclusion The peak value of cTnT andhs-CRP level are independent risk factors for MVO in STEMI patients,and have a certain predictive value to MVOoccurrence.
Keywords：Myocardial infarctionMicrovascular obstructionCardiac magnetic resonanceCardiac troponin THigh sensitivityC-reactive protein
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1000-1003 )