Improvement effect of cardiopulmonary exercise testing combined with impedance cardiography in guiding cardiac rehabilitation in patients with chronic heart failure
Lei Jiajia
Tan Ning
Song Menghong
Huang Ruijuan
Guan Kuaihuo
Abstract：Objective To discuss the improvement effect of cardiopulmonary exercise testing(CPET)combined with impedance cardiography(ICG)on heart function,cardiopulmonary response and exercisetolerance in guiding cardiac rehabilitation(CR)in patients with chronic heart failure(CHF).Methods The patients(n=180)with stable CHF were chosen and divided randomly into study group and control group(each n=90)from May 2021 to Aug.2023.The study group was given medication and exercise CR guided by CPET+ICG,and control group was given medication.The indexes of heart function,cardiopulmonary responses and exercise tolerance were detected at baseline and after intervention for 12 weeks.Results The indexes of resting heart rate(HR),anaerobic threshold(AT)-HR and peak HR decreased significantly(P＜0.05),AT-exercise duration,AT-maximal oxygen uptake(VO2max)/HR,increasingworking rate(WR)per minute,peak exercise time,peak VO2max/HR,peak load,VO2max/WR,△VO2max/△WR,average minute ventilation volume(VE)per 15 s/carbon dioxide output(VCO2),6-minute walk test(6MWT),restingmetabolic equivalents(METS)and peak METS increased significantly in study group after the intervention(P＜0.05).The indexes of AT-HR,peak HR decreased significantly(P＜0.05),and AT-VO2/HR increased significantly(P＜0.05)in control group after the intervention.The indexes of AT-exercise duration,AT-WR,peak exercise time,VO2max/HR,peak load,VO2max/WR,△VO2max/△WR,resting METS and peak METS were significantly higher in study group than those in control group after the intervention(P＜0.05).The indexes of cardiac output(CO),cardiac index(CI)and left ventricular ejection fraction(LVEF)increased significantly,and left atrial diameter(LAD),left ventricular end-diastolic diameter(LVEDD)and left ventricular end-systolic diameter(LVESD)decreased significantly in study group(P＜0.05),and CI increased and LAD decreased in control group(P＜0.05)after the intervention.LVEDD increased significantly in control group compared with study group after the intervention(P＜0.05).LVEF was positively correlated to △ VO2max/△ WR,and CI was positively correlated to AT-load,VO2max/HR and peak load(P＜0.05).LAD was negatively correlated to AT-load,resting METS,AT-VO2max/WR and △ VO2max/△ WR,LVDD was negatively correlated to resting METS and LVESD was negatively correlated to resting METS(P＜0.05).Conclusion ICG+CPET is conducive for developing the exercise scheme in CHF stable stage,and improving heart function and exercisetolerancein CHF patients.
Keywords：Cardiopulmonary exercise testingChronic heart failureCardiac rehabilitation
Publication Date：2024-07-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 793-797 )