Expression of heart rate variability and correlation among HRV,heart function and prognosis in patients with coronary heart disease complicated by acute heart failure
Yu Yan
Fu Dehua
Fang Chao
Abstract：Objective To investigate the expression of heart rate variability(HRV)and correlation among HRV,heart function and prognosis in patients with coronary heart disease(CHD)complicated by acute heart failure(AHF).Methods The patients with CHD complicated by AHF(n=63)were chosen into case group from Mudanjiang Hospital of Cardiovascular Diseases from Jan.2020 to Jan.2022.At the same time the patients with AHF only were chosen into AHF group(n=50)and healthy controls were chosen into control group(n=50).The patients were divided,according to occurrence of adverse cardiac events,into good prognosis group(n=45)and poor prognosis group(n=18).The changes of HRV were analyzed in all groups,and relationship among HRV,heart function and prognosis were analyzed.Results The levels of standard deviation of all normal RR interval(SDNN),root mean square of successive differences in RR interval(rMSSD),low-frequency component(LF)and high-frequency component(HF)were significantly lower,and LF/HF was significantly higher in case group than those in AHF group and control group.The levels of SDNN,rMSSD,LF and HF were significantly lower,and LF/HF was significantly higher in AHF group and control group(P＜0.05).The levels of SDNN,rMSSD,LF and HFwere significantly higher,and LF/HF was significantly lower in patients with grade Ⅱ of NYHA classification than those in patients with grades Ⅲ and Ⅳ.The levels of SDNN,rMSSD,LF and HFwere significantly higher,and LF/HF was significantly lower in patients with grade Ⅲ than those in patients with grade Ⅳ(P＜0.05).The levels of SDNN,rMSSD,LF and HFwere significantly higher,and LF/HF was significantly lower in good prognosis group than those in poor prognosis group(all P＜0.05).The results of Spearman correlation coefficient analysis showed that SDNN,rMSSD,LF and HF were negatively correlated to heart function and prognosis,and LF/HF was positively correlated to heart function and prognosis in patients with CHD complicated by AHF.Conclusion The expression of HRV was abnormal and closely related to heart function and prognosis in patients with CHD complicated by AHF,which opens a new way for the prevention and treatment of CHD complicated by AHF.
Keywords：Coronary heart diseaseAcute heart failureHeart rate variabilityHeart function
Publication Date：2024-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 730-732,738 )