Predictive value of myocardial activity evaluated by dual nuclide myocardial imaging to prognosis in patients with acute myocardial infarction
Li Xiaohong
Qin Yongde
Zhang Qizhou
Bu Guosen
Wang Jiao
Liu Zhiqiang
Abstract：Objective To investigate the predictive value of dual nuclide myocardial imaging to long-term major adverse cardiovascular events(MACE)in patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI).Methods AMI patients(n=95)were retrospectively chosen from the First Affiliated Hospital of Xinjiang Medical University from Jan.2015 to Dec.2020,and they were followed up for 3 y.All patients were divided,according to MACE occurrence after PCI,into MACE group(n=42)and control group(n=53).The differences in clinical characteristics and parameters related to dual nuclide myocardial imaging were compared between 2 groups.The predictive value of parameters related to dual nuclide myocardial imaging to MACE was analyzed.Results The incidence of diabetes increased significantly(42.86％vs.22.64％,P=0.035),severity of coronary stenosis increased significantly[(73.67±11.57)％vs.(66.11±8.69)％,P＜0.001],left ventricular ejection fraction(LVEF)decreased significantly(47.45±3.83 vs.52.13±4.31,P＜0.001),the total score of myocardial ischemia increased significantly[(14.29±4.20)％vs.(9.89±3.33)％,P＜0.001],and mismatch percentage of myocardial perfusion/metabolism increased significantly(16.58±1.61 vs.15.69±2.14,P=0.028)in MACE group compared with control group.LVEF had some predictive value to MACE after PCI(AUC=0.777,95％CI:0.686～0.868,P＜0.001).The severity of coronary stenosis and the total score of myocardial ischemia had some predictive value to MACE after PCI(AUC=0.676,AUC=0.784).The results of multi-factor Logistics regression analysis showed that LVEF＜50％and the total score of myocardial ischemia＞12 were independent risk factors of MACE within 3 y after PCI in AMI patients(P＜0.05).Conclusion The parameters related to dual nuclide myocardial imaging can be taken as one of predictive indicators for MACE in AMI patients after PCI.
Keywords：Acute myocardial infarctionPercutaneous coronary interventionDual nuclide myocardial imagingMajor adverse cardiovascular events
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 462-465 )