Clinical characteristics and related risk factors analysis of acute pulmonary embolism patients in Tai'an area
Zhou Qinghua
Zhang Yanqin
Qi Ximei
Zhou Houqiang
Zhao Jin
Du Bo
Song Zhaofeng
Abstract：Objective To analyze the epidemiological and clinical characteristics of hospitalized patients with APE in Tai'an area,and to explore the risk factors and peripheral blood biochemical characteristics of hospitalized patients with APE.Methods APE patients admitted to Tai'an Central Hospital from October 1,2016 to October 1,2021 were collected and grouped according to simplified risk Stratification Assessment Form(sPESI)for pulmonary embolism.Retrospective comparison of epidemiological characteristics,clinical manifestations,treatment,and prognostic outcomes between high-risk and non high-risk groups of patients.The APE study group was compared with the control group(healthy patients hospitalized during the same period),and the biochemical indexes such as white blood cell count,D-dimer,hypersensitive CRP apolipoprotein A1(apoA1)and echocardiogram data were analyzed for statistical and multiple logistic regression analysis to study the correlation between APE and the incidence and prognosis.Results Among 467 APE patients in this study,212 were males and 255 were females;In the past five years,the incidence rate has increased year by year,with the most significant incidence rate in winter.The main symptoms were dyspnea and shortness of breath,followed by cough,palpitation,chest pain,syncope and hemoptysis.The highest risk factors of APE patients in Tai'an city were lower limb venous thrombosis and varicose veins,followed by hypertension.Computed tomography pulmonary angiography(CTPA)combined with static echocardiography(UCG)can improve the clinical diagnostic rate of diseases.The proportion of pulmonary hypertension and right ventricular enlargement in the high-risk group was higher than that in the non high-risk group.All confirmed patients received anticoagulation treatment at the beginning of treatment(excluding those who were unable to anticoagulate),with 392 cases improving,1 1 deaths,and 29 cases automatically discharged.Smoking,age,hypotension or shock,difficulty breathing,pleural effusion,pulmonary infection,and sPESI are independent risk factors for APE death.Conclusion Early anticoagulation is the effective treatment of APE.
Keywords：Acute pulmonary embolismClinical featuresRisk factors
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 446-451 )