Correlation between heart rate recovery after exercise and risk of sudden cardiac death:a Meta-analysis of cohort studies
Wang Chenyang
Xu Peng
Guo Zhirong
Wang Dongying
Li Junxia
Cao Xuebin
Abstract：Objective To analyze comprehensively the correlation between heart rate recovery(HRR)after exercise and risk of sudden cardiac death(SCD)through a Meta-analysis.Methods The databases of PubMed,EMbase and Web of Science were retrieved up to Jan.2,2024.The cohort studies focused on the risk correlation between HRR and SCD,which was reviewed based on hazard ratio(HR)and 95％confidence interval(95％CI).All statistical analyses were conducted by using Stata 12.0 software.Results There were totally 6 studies included.The pooled results of fixed-effects model analysis(I2=41.8％,P=0.112)showed that SCD risk was lower in the patients with faster HRR than that in those with slower HRR(HR=0.74,95％CI:0.64～0.86,P＜0.001).The persistent results were observed in most subgroup analyses.After excluded a study,the overall result was not affected[HR(95％CI):0.66(0.55,0.79)to 0.76(0.65,0.88)].The results of Egger test showed that there was no significant publication bias(P=0.059).Conclusion The slower HRR can increase SCD risk,so HRR may be a potential target for SCD prevention in clinical practice.
Keywords：Sudden cardiac deathHeart rate recovery after exerciseMeta-analysisRisk correlation
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 398-402 )