Characteristics of myocardial magnetic resonance imaging and influence of late gadolinium enhancement on prognosis in patients with peripartum cardiomyopathy
Xu Yawei
Han Bin
Xu Haojie
Meng Yuan
Yang Haibo
Abstract：Objective To study the characteristics of myocardial magnetic resonance imaging(MRI)and influence of late gadolinium enhancement(LGE)on prognosis in patients with acute phase peripartum cardiomyopathy(PPCM).Methods The clinical materials and MRI characteristics of patients(n=22)with acute phase PPCM undergone myocardial MRI were retrospectively analyzed in the First Affiliated Hospital of Zhengzhou University from Jan.2014 to June 2021.All patients were divided,according to whether there was LGE in myocardial MRI or not,into positive LGE group(n=17)and negative LGE group(n=5).The clinical characteristics,myocardial MRI features,treatment and major adverse cardiovascular events(MACE)occurred during hospitalization.Results Among myocardial MRI of 22 patients with acute phase PPCM,the incidence rate of LGE was 77.3%.The baseline clinical materials had no statistical difference between 2 groups.The value of ejection fraction(EF)of myocardial MRI was lower in positive LGE group[20.74(17.57,33.55)%vs.34.58(27.72,47.41)%,P=0.026].There were 2 cases of major adverse cardiovascular events(MACE)in positive LGE group and there was no MACE case in negative LGE group.Except of 1 case died,there were 16 patients in positive LGE group and 5 patients in negative LGE group received follow-up of echocardiography,and EF value was(53.88±11.19)%vs.(61.00±2.35)%(P=0.028).The heart function recovered in 10 cases(62.5%)in positive LGE group and in 4 cases(80.0%)in negative LGE group.The value of EF was significantly higher in negative LGE group.The percentage of patients with recovered heart function were higher in negative LGE group than those in positive LGE group after follow-up,but had no statistical difference between 2 groups.Conclusion LGE is common in myocardial MRI in patients with acute phase PPCM,and LGE indicates lower EF in the future.
Keywords：Peripartum cardiomyopathyMyocardial magnetic resonance imagingLate gadolinium enhancement
Publication Date：2024-03-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 312-315 )