Effects of aerobic exercise rehabilitation on cardiopulmonary function in patients after percutaneous coronary intervention for chronic total occlusion
Gao Zhen
Chen Jieqiong
Zhou Ming
Cao Zheng
Abstract：Objective To explore the effect of aerobic exercise rehabilitation on cardiopulmonary function in patients with Chronic Total Occlusion(CTO)following Percutaneous Coronary Intervention(PCI).Methods From January 2019 to December 2021,43 patients diagnosed with CTO and successfully treated with PCI at the Cardiovascular Diagnosis and Treatment Center of Taihe Hospital in Shiyan City were enrolled.They were randomly divided into the routine group(n=22)and the exercise rehabilitation group(n=21).The routine group received standardized drug treatment for coronary heart disease and health education,while the exercise rehabilitation group underwent fixed bicycle exercise training based on the routine group at an anaerobic threshold intensity for 30～40 minutes/session,5～7 sessions/week.Cardiopulmonary exercise tests were performed at one week and six months post-surgery,and the changes in maximum oxygen uptake(VO2max),maximum oxygen uptake per kilogram(VO2max/kg),metabolic equivalent(METs),carbon dioxide ventilation equivalent slope(VE/VCO2 slope),minute ventilation(VE),work efficiency(VO2/WR),oxygen pulse(VO2/HR),peak heart rate(HRPeak),and oxygen uptake per kilogram at the anaerobic threshold(AT)were compared.Results At baseline,there were no significant differences in VO2max,VO2max/kg,METs,VE/VCO2 slope,VE,VO2/WR,VO2/HR,HRpeak,and AT between the two groups of subjects(P>0.05).Compared with baseline,there were no significant changes in these indicators in the standard care group at 6 months post-treatment(P>0.05).However,in the exercise rehabilitation group,VO2max,VO2max/kg,METs,VE,VO2/WR,VO2/HR,HRpeak,and AT showed significant improvement at 6 months post-treatment compared to baseline(P<0.05).When comparing between the two groups of subjects,after exercise intervention,VO2max,VO2max/kg,METs,VE,VO2/WR,VO2/HR,and AT in the exercise rehabilitation group were significantly improved compared to the standard care group(P<0.05),while there were no significant changes in VE/VCO2 slope and HRpeak(P<0.05).Conclusion Aerobic exercise training can effectively improve cardiopulmonary function in CTO patients after PCI,and it is a safe and effective cardiac rehabilitation program for CTO patients after PCI.
Keywords：Chronic Total OcclusionPercutaneous Coronary InterventionCardiopulmonary Exercise TestAerobic exercise
Publication Date：2024-03-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 296-299,303 )