Influence of obstructive sleep apnea hypopnea syndrome on heart function,heart rate variability and prognosis in patients with heart failure
Wang Qiao
Sun Fang
Cui Lina
Abstract：Objective To investigate the influence of obstructive sleep apnea hypopnea syndrome(OSAHS)on heart function,heart rate variability(HRV)and prognosis in patients with heart failure(HF).Methods The patients with acute HF(n=140)were chosen from Municipal Hospital of Qingdao City from Mar.2021 to Mar.2024.All patients were divided into OSAHS group(n=59)and non-OSAHS group(n=81).The data of sleep apnea hypopnea index(AHI),nighttime minimum blood oxygen saturation(SaO2),left ventricular ejection fraction(LVEF),brain natriuretic peptide(BNP),standard deviation of RR intervals for the total sinus beats(SDNN),standard deviation of average RR intervals(SDANN),root mean square of differences between adjacent RR intervals(RMSSD),percentage of number of adjacent NN intervals differing more than 50 ms in the total number of sinus beats(PNN50)and prognosis were compared between 2 groups.Results The levels of AHI and BNP were higher,and nighttime minimum SaO2 and LVEF were lower in OSAHS group than those in non-OSAHS group(P<0.05).SDNN,SDANN,RMSSD and PNN50 were lower in OSAHS group than those in non-OSAHS group(P<0.05).The results of follow-up showed that incidence rates of adverse cardiovascular events were higher in OSAHS group than those in non-OSAHS group(P<0.05).Conclusion OSAHS can affect heart function,HRV and shot-term prognosis in HF patients,which should be paid attention to in clinical practice.
Keywords：Heart failureSleep apnea hypopnea indexHeart functionHeart rate variabilityPrognosis
Publication Date：2024-02-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 221-223,226 )