The impact of weight loss surgery on atrial fibrillation risk:a CHARGE-AF model evaluation
Peng Ronggang
Meng Weilun
Gao Qizhong
Qu Shen
Zhang Yi
Xu Yawei
Wang Xiaoyan
Abstract：Objective To evaluate the impact of bariatric surgery on the risk of atrial fibrillation(AF)in obese patients using the CHARGE-AF model.Methods Obese patients who underwent laparoscopic sleeve gastrectomy(LSG)between August 2016 and May 2020 were included in this study.The relevant medical history,physical examination,and electrocardiogram results before and after LSG were collected and recorded,and the risk of AF was calculated using the CHARGE-AF model and CHARGE-AF enhanced model formula.Results A total of 67 participants were included in the study,with a mean follow-up time of 11.11±5.51 months.After LSG,there was a significant decrease in weight,systolic blood pressure,diastolic blood pressure,the rate of antihypertensive drug use,diabetes prevalence,myocardial hypertrophy incidence,and PR interval<120 ms incidence.However,there was no significant change in smoking rate,heart failure incidence,myocardial infarction incidence,or PR interval>199 ms incidence.According to the CHARGE-AF model formula,there was a decreasing trend in AF risk among participants[(0.11±0.10)%to(0.08±0.08)%,(P=0.07)].According to the CHARGE-AF enhanced model,the risk of AF was significantly reduced[(0.12±0.12)%to(0.08±0.08)%,(P<0.05)].When weight was included as a single-factor variable in the model,the risk of AF in participants was significantly reduced(P<0.001).Conclusion The possible risk factors for AF in obese patients,such as weight,blood pressure,and ventricular hypertrophy,were significantly improved after weight loss surgery,and the risk of AF was significantly reduced.
Keywords：CHARGE-AF modelObesityBariatric surgeryRisk evaluation
Publication Date：2024-02-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 198-201 )