The diagnostic value of Q-T interphase electrocardiogram combined with echocardiography in pulmonary hypertension and its correlation with disease severity
Zhang Jie
Li Changshuan
Qin Bo
Xue Jing
Abstract：Objective To investigate the diagnostic value of Q-T interphase electrocardiogram combined with echocardiography in pulmonary hypertension and its correlation with disease severity.Methods Clinical data of 80 patients with pulmonary hypertension in the First Affiliated Hospital of Henan University of Science and Technology from January 2020 to January 2023(pulmonary hypertension group)were retrospectively analyzed.Based on mean pulmonary arterial pressure(mPAP)determined by the right cardiac catheter,the severity of the disease was classified as mild(25～35 mmHg),moderate(36～45 mmHg),and severe(>45 mmHg).Eighty healthy subjects in the same period were selected as a control group.Ecg and echocardiography were performed in both groups,and the changes in corrected Q-T interval(Q-Tc)and Pulmonary artery systolic pressure(PASP)were compared.Multivariate Logistic regression analysis was used to analyze the relationship between Q-Tc,PASP,and the occurrence and severity of pulmonary hypertension.The diagnostic value of Q-Tc and PASP alone and combined in pulmonary hypertension was analyzed by the receiver operating characteristic(ROC)curve.Results Compared with the control group,Q-Tc and PASP in the pulmonary hypertension group were increased(P<0.05).The comparison of Q-Tc and PASP in the pulmonary arterial hypertension group was lower than moderate and severe,and moderate was lower than severe(P<0.05).Multivariate Logistic regression analysis showed that Q-Tc and PASP were important factors affecting the occurrence and severity of pulmonary hypertension(P<0.05).ROC curve showed that Q-Tc and PASP detection had certain diagnostic value for pulmonary hypertension,and the combined detection had higher diagnostic values.The sensitivity was 81.25%,the specificity was 77.50%,and the area under the ROC curve was 0.897.Conclusion Electrocardiogram Q-Tc combined with echocardiography has high diagnostic values in pulmonary hypertension and is closely related to the severity of the disease.
Keywords：Pulmonary hypertensionElectrocardiogramEchocardiographyDiagnosis
Publication Date：2024-02-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 149-152,158 )