Influence of Yandan Capsule combined with atorvastatin on platelet function and inflammatory factors in elderly patients with myocardial infarction
Han Bingmei
Li Hanying
Abstract：Objective To observe the influence of Yandan Capsule combined with atorvastatin on platelet function and inflammatory factors in elderly patients with acute myocardial infarction(AMI).Methods Elderly AMI patients(n=115)were chosen from Hospital of Traditional Chinese Medicine of Nanyang City from Aug.2018 to Aug.2020.The patients were divided,according to therapies,into control group(n=56)treated with atorvastatin orally and study group(n=59)treated with Yandan Capsule combined with atorvastatin from 30 d.The changes of symptom integrals,CD62p,CD63,monocyte platelet aggregates(MPA)and serum inflammatory factor[tumor necrosis factor-α(TNF-α)]were compared between 2 groups before and after treatment.The total curative effect was compared between 2 groups.Results The total effective rate was 89.83%in study group and 75.00%in control group(P<0.05).The comparison in symptom integrals of traditional Chinese medicine before and after treatment showed that integral reduction was significantly higher in study group than that in control group(P<0.05),and reduction of TNF-α was significantly higher in study group than that in control group(P<0.05).Conclusion Yandan Capsule combined with atorvastatin has a definite curative effect on elderly myocardial infarction,which can improve the related symptoms of qi deficiency and blood stasis,inhibit platelet activation,improve heart function,reduce level of serum inflammatory factor,and improve curative effect.
Keywords：Myocardial infarctionAtorvastatinPlateletSerum inflammatory factorsSenile
Publication Date：2024-01-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 56-59 )