Influence factors of heart failure in patients with acute anterior myocardial infarction after emergency PCI during hospitalization
Xu Tao
Tan Hongbin
Wang Zhi
Xie Weixing
Wu Jiehua
Abstract：Objective To investigate the risk and protective factors of heart failure(HF)in patients with acute anterior myocardial infarction(AAMI)after emergency percutaneous coronary intervention(PCI)during hospitalization.Methods AAMI patients(n=60),with infarction site in proximal anterior descending branch of coronary artery,undergone PCI during hospitalization were chosen from Department of Cardiology in Huangshan Shoukang Hospital from Jan.2019 to Dec.2022.The patients were divided,according to whether they suffered from HF during hospitalization or not,into HF group(n=32)and non-HF group(n=28).The clinical features were compared between 2 groups,and risk and protective factors of HF were analyzed by using multi-factor Logistic regression analysis.Results The levels of systolic blood pressure(SBP),diastolic blood pressure(DBP),percentages of pre-infarction angina and postoperative administration of ACEI/ARB/ARNI and postoperative TIMI flow grading all were lower(P<0.05),and age,percentage of diabetes,time from disease invasion to operation(h),level of serum creatinine(SCr),blood uric acid(BUA)and fibrinogen(FIB),and scores of self-rating anxiety scale(SAS)and self-rating depressive scale(SDS)all were lower(P<0.05)in HF group than those in non-HF group.The results of multi-factor Logistic regression analysis showed that pre-infarction angina(OR=0.214,95%CI:0.066～0.700,P=0.011)and higher postoperative TIMI flow grade(OR=0.227,95%CI:0.040～1.287,P=0.016)were protective factors of HF during hospitalization,and anxiety(OR=1.269,95%CI:1.078～1.494,P=0.004),depression(OR=1.127,95%CI:0.985～1.288,P=0.045),FIB(OR=4.316,95%CI:1.793～10.387,P=0.001),higher BUA(OR=1.013,95%CI:1.005～1.021,P=0.001)and longer time from disease invasion to operation(OR=1.122,95%CI:1.009～1.248,P=0.033)were risk factors of HF during hospitalization.Conclusion HF risk is lower in AAMI patients undergone emergency PCI with pre-infarction angina and better TIMI flow grade during hospitalization,and HF risk is higher in the patients with anxiety,depression,higher FIB,higher BUA and longer time from disease invasion to operation.
Keywords：Acute anterior myocardial infarctionHeart failureIntervention therapy
Publication Date：2024-01-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 32-34,44 )