Relationship between orifice area and mechanical function of left atrial appendage in patients with non-valvular atrial fibrillation
Xu Changjiang
Chen Lei
Zhang Chaoqun
Ding Yongguang
Zhou Bing
Gu Yang
Zhang Xiwen
Abstract：Objective To discuss the relationship between orifice area and mechanical function of left atrial appendage(LAA)in patients with non-valvular atrial fibrillation(NVAF).Methods NVAF patients(n=120)were chosen into the study,and among them there were 52 patients(43.3%)with paroxysmal atrial fibrillation(PAF group)and 68(56.7%)with persistent atrial fibrillation(PeAF group).The images were obtained by using computerized tomography angiography(CTA),and multiplanar reconstruction(MPR)was performed for getting LAA orifice area.Meanwhile LAA flow velocity(LAAFV)was detected by using transesophageal echocardiography(TEE).The relationship between LAA orifice area and LAAFV was analyzed in patients with different AF types.Results In PeAF group,larger LAA orifice area was closely correlated to lower LAAFV.The results of multi-factor Logistic regression analysis showed that LAA orifice area(P=0.009,OR=2.169,95%CI:1.217～3.867)and left atrial diameter(LAD,P<0.001,OR=1.514,95%CI:1.208～1.899)were independent predictive factors of lower LAAFV.In PAF group,there was no statistical correlation between LAA orifice area and LAAFV.Conclusion The predictive value of LAA orifice area to LAA mechanical function has difference in patients with different AF types.In PeAF patients,larger LAA orifice area and larger LAD are independent predictive factors of lower LAAFV,and in PAF patients this correlation was not observed.
Keywords：Atrial fibrillationArea of left atrial appendage orificeMechanical function of left atrial appendage
Publication Date：2023-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1220-1223,1232 )