Predictive value of HEARTS3 scoring system to major adverse cardiovascular events in patients with acute chest pain
Huang Zhiming
Liu Hong
Abstract：discuss the predictive value of HEARTS3 scoring system to major adverse cardiovascular events (MACE) in patients with acute chest pain in 30 d. Methods The patients with acute chest pain (n=620) were chosen from Department of Cardiovascular Medicine in People’s Hospital of Honghu City from Jan. 2016 to May 2019. All patients were given scored on risk degree by applying HEART and HEARTS3 scoring systems respectively. The incidence of MACE was followed up in 2 groups within 30 d after MACE attack. The relationship between scoring results and MACE incidence was analyzed, and predictive value to MACE was compared between 2 systems. Results There were 75 (12.10%) patients with MACE (MACE group), and 545 (87.90%) patients without MACE (non-MACE group). The average age was significantly elder in MACE group than that in non-MACE group, and male case proportion and incidence rates of diabetes, hypertension, smoking, dyslipidemia, history of myocardial infarction, family history of coronary heart disease and history of PCI were all significantly higher in MACE group than those in non-MACE group (P<0.05). There was no incidence of MACE in patients with low-risk HEART and HEARTS3 scores. The incidence rate of MACE was significantly higher in patients with high-risk HEARTS3 score than that in patients with high-risk HEART score, and was significantly lower in patients with middle-risk HEARTS3 score than that in patients with middle-risk HEART score (P<0.05). The results of ROC analysis showed that when HEART score was 6, AUC value was the highest (0.909), and sensitivity was 71.85% and specificity was 97.60%. When HEARTS3 score was 10, AUC value was the highest (0.974), and sensitivity was 85.82% and specificity was 97.82%. The specificity for predicting MACE was similar between HEART and HEARTS3 scoring systems (P>0.05). The predictive sensitivity of HEARTS3 scoring system for MACE was higher compared with that of HEART scoring system (P<0.05). Conclusion HEART and HEARTS3 scoring systems can be used in risk stratification in patients with acute chest pain, while HEART3 scoring system has higher sensitivity in predicting MACE risk.
Keywords：Major adverse cardiovascular eventsAcute chest painHEARTS3 scoring systemPredictive value
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1244-1247 )