Influence of glycated hemoglobin on long-term prognosis in patients with non-ST-segment elevation myocardial infarction undergone PCI
Hao Yuanyuan
Ma Feng
Li Tao
Ma Qiangqiang
Yang Guodong
Hu Peijing
Ma Aiqun
Abstract：discuss the relationship between level of glycated hemoglobin (HbAlc) and long-term prognosis in patients with non-ST-segment elevation myocardial infarction (NSTEMI) undergone PCI. Methods NSTEMI patients undergone PCI (n=890) were chosen from the First Affiliated Hospital of Xi’an Jiaotong University, Center Hospital of Xi’an City and People’s Hospital of Shaanxi Province from Jan. 2009 to Oct. 2012. All patients were divided, according to incidence of diabetes and HbA1c level, into 4 groups: group 1 (without diabetes and HbA1c<5.7%, n=417), group 2 (without diabetes and HbA1c from 5.7% to 6.5%, n=237), group 3 (with diabetes and HbA1c<7.0%, n=138), and group 4 (with diabetes and HbA1c≥7.0%, n=98). The incidence rates of major adverse cardiovascular events (MACE), all-cause mortality, death from cardiovascular causes, recurrent nonfatal myocardial infarction, re-hospitalization due to heart failure, re-revascularization and stroke were analyzed in all groups within 3 y after discharged from hospital. Results The incidence of MACE and mortality within 3 y were higher in group 2 than those in group 1 (all P<0.05). The incidence of MACE and mortality within 3 y had no significant difference between group 4 and group 3. The level of blood glucose was a risk factor of poor long-term prognosis in NSTEMI patients under gone PCI with or without diabetes. Conclusion The increase of HbA1c level is not the risk factors of MACE and mortality within 3 y in patients with NSTEMI complicated by diabetes undergone PCI, while it is the risk factors of MACE and mortality within 3 y in patients with NSTEMI without diabetes undergone PCI.
Keywords：Non-ST-segment elevation myocardial infarctionGlycated hemoglobinMajor adverse cardiovascular eventsMortality
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1174-1178,1187 )