Risk factors of major adverse cardiac events after percutaneous coronary intervention in elderly patients with acute coronary syndrome

Xie Nan; Li Jian; Xu Can.

doi:10.3969/j.issn.1674-4055.2019.09.24

Abstract：Objective To discuss and analyze the risk factors of major adverse cardiac events (MACE) after percutaneous coronary intervention (PCI) in elderly patients with acute coronary syndrome (ACS). Methods ACS patients (n=187) were chosen from the First Affiliated Hospital of Nanhua University from Jan. 2013 to Jan. 2016. All patients were divided, according to invasion of MACE, into MACE group (group A) and non-MACE group (group B). The risk factors of MACE after PCI were analyzed and studied. Results The incidence of MACE was 12.30% after PCI for 1 y and 15.51% within 2 y after PCI, and the total incidence of MACE was 27.81% within 2 y after PCI in elderly ACS patients. The results of single-factor analysis showed that there were statistical differences in age, hypertension, hyperlipidemia, diabetes, adjuvant medication, heart function grading, smoking, drinking, lesion vessels of coronary artery, total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C) and white blood cell count (WBC) between group A and group B (P<0.05). There were no differences in sex, living alone, first-time PCI, body mass index (BMI) and creatine kinase-MB isoenzyme (CK-MB) between 2 groups (P>0.05). The results of Logistic regression analysis showed that age, hypertension, hyperlipidemia, diabetes, adjuvant medication, lesion vessels of coronary artery, heart function grading, smoking, drinking, TC, LDL-C, HDL-C and WBC were important risk factors of MACE after PCI in ACS patients. Conclusion The incidence of MACE was higher after PCI in elderly ACS patients. The prognosis of the patients will be improved through changing unhealthy living habits and taking adjuvant medicines.