Comparison of long-term prognosis of patients with multivessel disease with acute non-ST-segment elevation myocardial infarction
Zheng Mei
Li Shuren
Sun Mingchao
Yang Lingling
Yang Guohui
Liu Xuan
Hao Xiao
Xiao Sa
Abstract：The effects of different treatments on long-term prognosis were compared of non-ST-segment elevation myocardial infarction with multivessel vessel disease. The different treatment methods include only dealing with culprit-only revascularization (COR) and one-time complete revascularization (CR). Methods A total of 140 patients treated in Hebei General Hospital from 2016-01 to 2018-05 were enrolled. According to the different treatment methods of NSTEMI combined with multivessel disease, the patients were excluded and the patients were divided into COR groups. (n=95) and CR group (n=35). Baseline data such as gender, age, smoking history, hypertension, diabetes, biochemical indicators, echocardiographic index, and interventional surgery related indicators were collected to compare the long-term prognosis of NSTEMI patients with multivessel disease. Results NSTEMI patients with multivessel disease were followed up for an average of 11.25 (5.38, 15.13) months. In the composite end point (all-cause death, recurrent myocardial infarction, revascularization, angina hospitalization), CR was compared with COR (8.57% vs. 6.32%, P=0.035), the difference was statistically significant. And there was a statistical difference between the two groups. In the secondary end point (angina recurrent, bleeding, arrhythmia, heart failure hospitalization, stroke), we compared one-time complete revascularization (CR) with culprit-only revascularization (48.58% vs. 23.15%, P=0.031). The difference between the two groups was still statistically significant. Conclusion For patients with NSTEMI complicated with multivessel disease, COR may be an ideal strategy and needs further confirmation in a multicenter, prospective, randomized controlled trial.
Keywords：Non-ST-segment elevation myocardial infarctionMultivessel vessel diseasePercutaneous coronary interventionCulprit vesselOne-time complete revascularization
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 746-749 )