Influencing factors in patients with coronary heart disease and concomitant ischemic stroke and predictive value of left atrium size

Zou Keyong; Li Dacheng; Sun Shaobing

doi:10.3969/j.issn.1674-4055.2019.06.24

Abstract：To analyze the influencing factors in patients with coronary heart disease (CHD) and concomitant ischemic stroke and predictive value of left atrium size. Methods CHD patients (n=97) were chosen from Department of Cardiology of Nanshi Hospital of Nanyang City from June 2013 to June 2017. The patient with only CHD were chosen into group A (n=46) and those with CHD and concomitant ischemic stroke were chosen into group B (n=51). The clinical baseline data were compared in 2 groups. The relevant factors influencing CHD complicated by ischemic stroke were analyzed by using Logistic regression analysis. The predictive value of different influencing factors was compared through drawing receiver operating characteristic (ROC) curve. Results The comparisons in gender, smoking history, medication status, concomitant hyperlipidemia history and concomitant diabetes history had no significant differences between the two groups (all P>0.05). The age, carotid plaque incidence and concomitant hypertension history were significantly higher in group B than those in group A (all P<0.05). The comparison in left ventricular diameter (LVD) showed no significant difference between 2 groups (P>0.05). The left atrial diameter (LAD) and left atrial diameter index (LADi) increased significantly (all P<0.05), and left ventricular ejection fraction (LVEF) decreased significantly (P<0.05) in group B compared with group A. The results of Logistic regression analysis showed that carotid plaque, concomitant hypertension history, LAD and LADi were influencing factors of CHD with concomitant ischemia stroke (all P<0.05), and the area under ROC curve was 0.68, 0.59, 0.86 and 0.89 respectively. Conclusion Carotid plaque, concomitant hypertension history, LAD and LADi are influence factors of CHD with concomitant ischemic stroke, and LAD and LADi with higher predictive value. So the left ventricular size can be considered to be included in review indexes of CHD with concomitant ischemic stroke in clinical practice.