Prediction efficiency of peripheral blood NLR for acute kidney injury in patients with acute ST-segment elevation myocardial infarction
Zhang Qianhui
Zhang Zhimei
Xie Yuetao
Dang Yi
Li Shuren
Abstract：To study the prediction efficiency of peripheral blood NLR for acute kidney injury in patients with acute ST-segment elevation myocardial infarction. Methods 98 patients with acute ST-segment elevation myocardial infarction admitted to Hebei General Hospital from February 2016 to February 2018 were as research objects. All patients were divided into acute kidney injury group (n=37) and non-acute kidney injury group (n=61) according to whether acute kidney injury occurred or not. The general data of the two groups, and the level of biochemical indexes and drug application was compared. The relationship between acute kidney injury and various factors in patients with acute ST-segment elevation myocardial infarction was analyzed by Multivariate logistic regression analysis. Results The age, the proportion of Killip grade was III to IV, and the number of diuretics used in acute kidney injury group was higher than those in non-acute kidney injury group (P<0.05). There was no significant difference in gender, smoking history, hypertension history, diabetes history, hyperlipidemia, coronary heart disease history (P>0.05). The level of NLR, CRP, NT-pro BNP and troponin I in acute kidney injury group was higher than that in non-acute kidney injury group, while the level of e GFR was lower than that in non-acute kidney injury group (P<0.05). Multivariate logistic regression analysis showed that NLR, the use of diuretics, CRP, e GFR, NT-pro BNP and troponin was the influencing factor of acute kidney injury in patients with acute ST-segment elevation myocardial infarction (all P<0.05).The ROC curve analysis showed that the area under the curve of NLR for predicting acute kidney injury was 0.838, the sensitivity was 81.5%, and the specificity was 74.2%. Conclusion Age, Killip grade, NLR, the use of diuretics, CRP, e GFR, NT - pro BNP, troponin was closely related to acute kidney injury in patients with acute ST-segment elevation myocardial infarction, and NLR is more effective in predicting acute kidney injury in patients with acute ST segment elevation myocardial infarction.
Keywords：Acute ST segment elevation myocardial infarctionAcute kidney injuryNeutrophilLymphocytesMultivariate logistic regression analysis
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 670-673 )