Relationship between left atrial diameter index and blood pressure variability in patients with essential hypertension

Feng Yijing; Zhu Limin; Duan Shaobo; Wang Huanxia; Li Shuaibing; Wan Zhen

doi:10.3969/j.issn.1674-4055.2019.04.16

Abstract：Objective To study the association of left atrial diameter index and blood pressure variability (BPV) in patients with essential hypertension. Methods Ninety patients with primary hypertension admitted to the outpatient department and inpatient department of Henan Provincial People's Hospital from January 2017 to January 2018 were enrolled. The left atrial diameter index (LADi) was measured by echocardiography and the patients were divided into observation groups. Left atrial enlargement, 22 cases) and control group (normal left atrium, 68 cases), all patients received dynamic blood pressure monitoring (ABPM), recording various blood pressure indicators, testing various blood biochemical indicators, and analyzing the correlation between indicators. Results The course of disease in observation group was significantly higher than that in control group (P<0.05), and the eGFR in observation group was significantly lower than that in control group (P<0.05). The 24h SBP, 24h DBP, 24h SSD, 24h wsdSBP, 24h wsdDBP, morning peak blood pressure (MBPS) and LADi in observation group were significantly higher than those in control group (all P<0.05). The descending rates of SBP and DBP were significantly lower than those in the control group (P<0.05). The course of disease, 24h SBP, 24h DBP, 24h wsdSBP, 24h wsdDBP, 24h DSD, MBPS were positively correlated with LADi (all P<0.05), while the decrease rate of SBP and DBP were negatively correlated with LADi (all P<0.05). Conclusion The LADi is related to the blood pressure variability in patients with essential hypertension. Detection of BPV is important for early detection of left atrial remodeling and reduction of adverse prognosis such as atrial fibrillation and stroke.