Correlation between age and morphology and volume of left atrial appendage in patients with atrial fibrillation
Zhang Baixiang
Xu Kai
Zhang Chaoqun
Zhang Fengyun
Li Chengzong
Chen Wensu
Wang Zhirong.
Abstract：Objective To study the relationship between age and morphology and volume of left atrial appendage (LAA), and influence factors on them. Methods The patients (n=238) undergone enhanced computerized tomography (CT) were chosen from the Affiliated Hospital of Xuzhou Medical from Jan. 2015 to June 2018, and their data was retrospectively analyzed. All patients were divided into atrial fibrillation group (AF group, n=110) and sinus rhythm group (SR group, n=128). CT was used to obtain images and morphology of LAA and left atrial appendage volume index (LAAVi) were obtained by using reconstructed 3-dimensional images. The morphology LAA and LAAVi were compared between 2 groups, and the relationship between them and age was analyzed. Results LAAVi increased with aging in AF group (P<0.001), but was not related to age in SR group (P=0.379). As LAAVi, the distribution of non-chicken wing LAA (non-CW LAA) decreased in 2 groups (P=0.004 vs. P=0.016). The distribution of non-CW LAA decreased with aging in AF group (P=0.003), and was not related to age in SR group (P=0.453). The results of single-and multiple-factor Logistic regression analysis showed that age over 65 (OR=0.485,P=0.005), AF course (OR=0.977,P=0.017) and LAAVi (OR=0.634, P<0.001) were independent influence factors of non-CW LAA in AF patients. Conclusion The prevalence of the non-CW LAA decreases with aging in patients with AF. When morphology of non-CW LAA is taken as a risk factor of stroke in AF patents, the effect of age should be paid attention to.
Keywords：Morphology of left atrial appendageLeft atrial appendage volume indexAtrial fibrillationAgeComputerized tomography
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 305-308 )