Related factors and predictability of high sensitivity C-reactive protein to perioperative cardiovascular events of diabetes
He Jizhong
Abstract：Objective To analyze the related factors to perioperative cardiovascular events (PCE) of diabetes, and discuss the value of level of high sensitivity C-reactive protein (hs-CRP) in veracity of PCE incidence prediction.Methods The diabetic patients (n=350) received non-cardiac operation were chosen from People's Hospital of Baoji City from Oct.2016 to Jan.2018, and divided, according to level of plasma hs-CRP, into lowdose group (hs-CRP＜1.0 mg/L, n=50), mid-dose group (hs-CRP 1.0～3.0 mg/L, n=75) and high-dose group (hs-CRP＞3.0mg/L, n=225).The correlation between single variable risk factor and PCE was analyzed by using Spearman rank correlation analysis.The risk factors related to PCE were analyzed in patients with P＜0.05 by using binary Logistic regression analysis, and veracity of risk factors in prediction of PCE was analyzed by using ROC curve in diabetic patients.Results The incidence of PCE was 0 in low-dose group.There were 10 cases of severe arrhythmia (13.33％) and 12 cases of myocardial ischemia (16％) in mid-dose group.There were 32 cases of severe arrhythmia (14.22％) and 18 cases of myocardial ischemia (8.07％) in high-dose group.The results of Logistic regression analysis showed that grades of heart failure, age, level of glycated hemoglobin (HbAlc), echocardiogram and hs-CRP were independent risk factors of PCE in diabetic patients (P＜0.05).The ROC of PCE in grades of heart failure was 0.385, 0.354 in HbAIc level, 0.819 in hs-CRP and 0.788 in echocardiogram.Conclusion The perioperative level of hs-CRP has some value in prediction of PCE in diabetic patients.
Keywords：DiabetesHigh sensitivity C-reactive proteinPerioperative periodCardiovascular events
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1571-1573 )