Influence of estimated glomerular filtration rate on prognosis in patients with acute myocardial infarction after primary percutaneous coronary intervention
Zhao Shengji
Liu Chaoquan
Zheng Weimin
Abstract：Objective To analysis between the changes of estimated glomerular filtration rate (eGFR) and major adverse cardiovascular events (MACE) in patients with acute myocardial infarction (AMI) after primary percutaneous coronary intervention (PCI), and to help to improve patients'outcomes.Methods AMI patients (n=86) were chosen continuously from Department of Cardiology of Hainan Western Central Hospital from Jan.2014 to Dec.2016.All patients were divided, according to changes of eGFR, into normal eGFR group (eGFR＞90.0ml/min·1.73 m2) and abnormal eGFR group (eGFR＜90.0 ml/min·1.73 m2).The general data, results of coronary angiography (CAG) and incidence of MACE were recorded and compared between 2 groups, and the influencing factors of MACE were analyzed by using Cox proportional hazards regression model.Results The comparisons in numbers of diseased coronary vessels, infarction-related arteries and complicating lesions of left main coronary artery (LMCA) showed that the difference had no statistical significance between 2 groups (P＞0.05).The total incidence of MACE was significantly higher in abnormal eGFR group than that in normal eGFR group (P＜0.05).The analysis results of Cox proportional hazards regression model showed that age, diabetes and eGFR were risk factors of MACE occurrence (P＜0.05).Conclusion When the level of serum creatinine is in reference range, the decreased eGFR has a higher predictive value to MACE occurrence in AMI patients after primary PCI.The patients with MACE risks will be intervened for improving their prognosis.
Keywords：Acute myocardial infarctionEstimated glomerular filtration ratePrimary percutaneous coronary interventionPrognosisCoronary artery
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1534-1536,1539 )