A comparison between Shugan Jieyu Capsule and escitalopram oxalate in treatment of hypertension complicated by anxiety-depression
Sun Yi
Tian Guoxiang
Shi Kewei
Sun Xianmin
Li Xueyong
Zeng Wei
Li Huixian
Zhang Bin
Tian Fuli
Abstract：Objective To investigate the curative effect and safety of Shugan Jieyu Capsule and escitalopram oxalate combined respectively with anti-hypertension drugs in patients with hypertension complicated by anxietydepression.Methods The patients (n=100) were chosen from Department of Cardiology in Chinese PLA 251Hospital from July 2017 to July 2018, and randomly divided into observation group and control group (each n=50).Besides of routine treatment, the observation group was given Shugan Jieyu Capsule and control group was given escitalopram oxalate.Results After treatment for 6 weeks, systolic blood pressure and diastolic blood pressure decreased significantly in 2 groups without statistical difference (P＞0.05).The scores of anxiety and depression decreased significantly in 2 groups without statistical difference (P＞0.05).The incidence of adverse reactions was10％in observation group and 30％in control group (P＜0.05).Conclusion Shugan Jieyu Capsule and escitalopram oxalate have significant curative effect in patients with hypertension complicated by anxiety-depression, the incidence of adverse reactions of Shugan Jieyu Capsule is lower than that of escitalopram oxalate.
Keywords：HypertensionAnxietyDepressionShugan Jieyu CapsuleEscitalopram oxalate
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1478-1479,1487 )