Comparison in long-term curative effects of radiofrequency ablation and antiarrhythmic drugs in treatment of persistent atrial fibrillation
Gao Yingchun
Wu Yuntao
Zhao Ping
Jiang Peng
He Liping
Zhang Ying
Abstract：Objective To compare the long-term curative effects of radiofrequency ablation (RFA) and antiarrhythmic drugs (AAD) in treatment of persistent atrial fibrillation (AF).Methods The patients with persistent AF (n=60), with disease course from 3 months to 9 months and left atrial anteroposterior diameter＜45 mm and LVEF＞50％, were chosen from Department of Cardiology in People's Hospital of Inner Mongolian Autonomous Region from Jan.2010 to Mar.2016.The patients were divided, according to therapeutic methods, into RFA group (n=30) received RFA treatment including circumferential pulmonary vein isolation and linear ablation, and control group (n=30) treated with AAD.All patients were followed up for an average 3 y after treatment.Whether the patients could maintain sinus rhythm for long time was analyzed in 2 groups after discharged from hospital.Results There were 23 male cases and 7 female cases aged from 47 to 72 with an average age= (59.8±7.1) years old in RFA group.There were 20 male cases and 10 female cases aged from 48 to 73 with an average age= (62.8±6.5) years old in control group.The difference in sex, age, left atrial diameter (LAD) and LVEF had no statistical significance between 2 groups (all P＞0.05).The long-term effective rate was 46.7％in RFA group and 16.7％in control group (P=0.012).Conclusion The long-term effective rate is higher in patients with persistent AF treated with RFA than that in those treated with AAD.
Keywords：Persistent atrial fibrillationRadiofrequency ablationAntiarrhythmic drugs
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1475-1477 )