Effect of milrinone nebulization therapy in children with heart failure
Yu Xia
Yuan Yue
Sun Chenglei
Liu Xinling
Cheng Guoliang
Xu Jian
Xu Aifeng
Abstract：Objective To investigate the effect of milrinone inhalation on heart function in children with heart failure for 7 days. Methods A total of 50 children with heart failure who were admitted to the Department of Cardiology of Beijing Children's Hospital from June 2015 to June 2017 were enrolled. The patients were treated with conventional anti-heart failure treatment. The heart rate, respiration, blood pressure, brain natriuretic peptide (BNP), cardiac function index and adverse reactions during treatment were recorded before and after treatment with milrinone. Results After 7 days of milrinone inhalation treatment, the effective rate was 48.0%, the effective rate was 42.0%, and the total effective rate was 90.0%. Compared with milrinone before nebulization, the left ventricular ejection fraction after nebulization (t=3.718, P<0.05), the difference of BNP was statistically significant (P<0.05). There was no significant difference in heart rate and blood pressure (P>0.05). Conclusion Short term nebulization of milrinone treatment can improve the heart function in children with heart failure. It is a safe and effective, with high compliance and promotion method.
Keywords：MilrinoneNebulization therapyIntravenous infusionHeart failureChildren
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1348-1350 )