Correlation between carotid atherosclerosis and coronary atherosclerosis in patients with coronary heart disease

Li Jing; Zhang Mingzhi; Zhang Xun; Liu Jiakai; Luo Li

doi:10.3969/j.issn.1674-4055.2018.05.18

Abstract：Objective To study the intima-media thickness (IMT) of carotid artery by ultrasonography, and to analyze the correlation between Gensini score of coronary atherosclerosis and Crouse score of carotid atherosclerosis, and to provide evidence for the prevention and treatment of coronary heart disease (CHD). Methods A total of 114 patients undergoing coronary angiography (CAG) examination from January 2015 to January 2017 were enrolled. According to the results of CAG test, 114 cases were divided into non CHD group (n=40) and CHD group (n=74). According to the number of coronary lesions, the CHD group were divided into three subgroups. Carotid artery IMT and carotid plaque Crouse scores of non-coronary heart disease group and coronary heart disease group were compared to discuss the relationship between Gensini score and Crouse score; and the clinical value of carotid ultrasound in the diagnosis of coronary heart disease was evaluated. Results The IMT of CHD group was thicker than that of non CHD group, and the difference was statistically significant (P<0.05). The IMTs of the three subgroups (single branch, two branch and three subgroup) were 0.94±0.15 mm, 1.17±0.17 mm and 1.21±0.23 mm. Crouse score of non CHD group was 1.11. The Gensini score of non CHD group was (0.0±0.0). The Crouse score of CHD group was (5.14±3.41), Gensini score of CHD group was (22.2±11.02). The above indexes in CHD group were higher than those of non CHD group (P<0.05). The correlation analysis showed that the Crouse integral was positively correlated with the Gensini score (r=0.354, P=0.001). The diagnostic accuracy of carotid ultrasound diagnosis of CHD was 86.0%. Conclusion The correlation between the severity of coronary atherosclerosis and the degree of carotid atherosclerosis can be diagnosed by using the indexes of carotid ultrasonography, and it is practical and worthy of clinical promotion.