Relationship between serum uric acid and heart-iliac vascular index (CAVI) in patients with type 2 diabetes mellitus
Sun Yi
Liu Hui
Li Ping
Wang Yinna
Abstract：Objective To investigate the correlation between serum uric acid level and heart-ankle vascular index (CAVI) in type 2 diabetic patients. Methods 135 patients with type 2 diabetes and without diabetic nephropathy were enrolled. We recorded the general clinical data, blood biochemical indicators, and CAVI. The patients were divided into four groups according to CAVI quartile. The relationship between CAVI and serum uric acid and the correlation between CAVI and CAVI were analyzed. Result ①CAVI median 9.45, according to CAVI quartile patients were divided into four groups, respectively: Q1≤8.2, 36 cases; Q2: 8.2~9.45, 34 cases; Q3:9.45~10.45, 33 cases ; Q4≥10.45, 32 cases. There were significant differences in age, body mass index (BMI), low density lipoprotein cholesterol (LDL-C), estimated glomerular filtration rate (eGFR) between the four groups (P<0.05). ②SUA level was higher than that of Q1, Q2 and Q3 groups (P<0.05). There was a positive correlation between serum uric acid and CAVI in patients with diabetes mellitus (r=0.365, P<0.01). ③The level of CAVI was positively correlated with age and negatively correlated with eGFR (r=-0.215, P<0.05). Conclusion Serum uric acid has a certain effect on arteriosclerosis in type 2 diabetes mellitus patients. Decreased early eGFR in diabetic patients with normal serum creatinine may be one of the risk factors of atherosclerosis.
Keywords：Serum uric acidType 2 diabetes mellitusAtherosclerosis
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 572-574 )