Risk factors of short-term mortality in patients with severe acute coronary syndrome treated with adjuvant intraaortic balloon pumping
Wu Guoliang
Yan Rongqiang
Liu Gang
Yang Lu
Wang Haiyang
Geng Qiang
Ren Yongqiang
Fan Shuxin
Zhang Junyi
Wang Zhengzhong
Yu Zhongxiang
Chi Yifan
Abstract:Objective To discuss the influencing factors of adjuvant intraaortic balloon pumping (IABP) on 30-d death in patients with severe acute coronary syndrome (ACS). Methods The patients with severe ACS (n=239), among them female were 70 (19.3%), were chosen from Qingdao Municipal Hospital from Oct. 2014 to May 2017. All patients were divided, according to 30 d survival state, into 30 d survival group (n=198) and 30 d death group (n=41). The general data was compared between 2 groups, and risk factors of 30 d death were analyzed by using single-factor and multi-factor binary Logistic regression analysis. Results Compared with 30 d survival group, the percentages of female, cases of ST-segment elevation myocardial infarction (STEMI), cardiogenic shock and treated with drug conservative therapy were higher, and heart rate was faster in 30 d death group (all P<0.05). The percentages of patients treated with coronary artery bypass grafting (CABG) and pretreatment of IABP were lower in 30 d death group (all P<0.05). The results of multi-factor binary Logistic regression analysis showed that percutaneous coronary intervention (PCI) is a protective factor of 30 d death in ACS patients treated with adjuvant IABP (OR=0.28, 95%CI: 0.08~0.94, P=0.039). Female (OR=2.45, 95%CI: 1.01~5.92, P=0.047) and cardiogenic shock (OR=7.86, 95%CI: 2.83~21.81, P<0.001) were independent risk factors of 30 d death in ACS patients treated with adjuvant IABP. Conclusion PCI is a protective factor, and female and cardiogenic shock are independent risk factors of 30 d death in ACS patients treated with adjuvant IABP. During the therapeutic course, cardiogenic shock should be corrected actively and PCI is chosen as far as possible especially for female patients.
Keywords:Acute coronary syndromePercutaneous coronary interventionCoronary artery bypass graftingIntraaortic balloon pumping
Publication Date:2018-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 454-457 )