Effects of Deproteinized Calf Serum Injection on Neurological Function and Activities of Daily Living in Patients with Cerebral Embolism Caused by Atrial Fibrillation
Peng Yanhui
Abstract：Objective To observe the impacts of deproteinized calf blood serum injection on the neurological function impairment and activity of daily living of patients with cerebral embolism caused by atrial fibrillation, and the safety. Methods 73 cases were randomly divided into study group (38 cases) and control group (35 cases), they were both treated by Argatroban (10~30 mg/d), Edaravone (30 mg each time, once a day) and Mannitol (125 ml each time, 1/6 h), intravenous drip. The study group received deproteinized calf blood serum injection (20 ml each time, once a day) additionally. All treated for 14 days. National Institute of Health Stroke Scale (NIHSS) score and Barthel index (BI) were calculated to assess the neurological function impairment and activity of daily living, respectively. Taking NIHSS as the main reference index, the clinical efficacy of the two groups was compared, and the adverse effects of liver and kidney function, blood and urine routine and electrocardiogram were recorded. Results There was no significant difference in the general data between the two groups (P>0.05). After treatment, as compared with those in the control group, NIHSS score was significantly reduced and BI score was increased in the study group (P<0.05). The clinical efficiency was 85.46% in the study group, which was higher than 64.88% of control group. No obvious adverse reaction was recorded. Conclusion Deproteinized calf blood serum injection could improve the neurological function impairment and activity of daily living of patients with cerebral embolism caused by atrial fibrillation.
Keywords：Atrial fibrillationCerebral embolismDeproteinized calf blood serum injection
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 425-427 )