Influence of revascularization of percutaneous coronary intervention on left ventricular myocardial remodeling in patients with chronic total occlusion of coronary artery
Yang Bo
Deng Yunchao
Tan Liguo
Zhang Lei
Tang Junming
Wang Jianing
Abstract：Objective To discuss the influence of revascularization by percutaneous coronary intervention (PCI) on left ventricular myocardial remodeling in patients with chronic total occlusion (CTO) of coronary artery. Methods The inpatients were chosen from Department of Cardiology of People's Hospital affiliated to Hubei University of Medicine from Sept. 2015 to June 2017, among them 62 were diagnosed as CTO and received revascularization by PCI. The patients were followed up for about 1 y, and their baseline information and data of echocardiography and serology were collected and analyzed by using SPSS20.0 software. Results Compared with baseline data, the levels NT-pro BNP [(295.25±468.90) pg/ml vs. (492.90±840.25) pg/ml, P=0.001], LDL [(1.94±0.65) mmol/L vs. (2.41±0.93) mmol/L, P<0.001], TG [(1.33±1.02) mmol/L vs. (1.52±1.02) mmol/L, P=0.018] and TC [(3.25±0.79) mmol/L vs. (4.15 ±1.12) mmol/L, P<0.001] decreased significantly after revascularization for 1 y. Compared with baseline data, the level of NT-pro BNP was significantly lower in 1-vessel disease subgroup than that in multi-vessel disease subgroup [(254.9±381.6) pg/ml vs. (515.2±600.5) pg/ml, P=0.027], and was significantly lower in non-coronary collateral circulation subgroup than that in coronary collateral circulation subgroup [(210.65±279.05) pg/ml vs. (457.65± 559.48) pg/ml, P=0.040] after revascularization for 1 y. Conclusion The revascularization by PCI can promote heart function through improving left ventricular myocardial remodeling in CTO patients, and those with single vessel disease or non-collateral circulation can obtain more benefit.
Keywords：Coronary artery lesionChronic total occlusionInterventional therapyVentricular remodelingSingle-vessel diseaseCollateral circulation
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 410-413,417 )