Risk factors of perioperative cardiac events in hypertensive patients undergone non-cardiac surgery
Ding Yanling
Liang Lunchang
Liang Maojin
Tan Qiping
Chen Weiquan
Liang Jianwen
Abstract：Objective To investigate the independent risk factors of perioperative cardiac events in hypertensive patients undergone non-cardiac surgery. Methods Hypertensive patients (n=245, male 123 and female 122) were chosen from Jan. 2012 to Dec. 2016. All patients received time-selected non-cardiac surgery. The patients were divided, according to cardiac event occurring state, into cardiac event group (n=55) and non-cardiac event group (n=190). The data of medical records, including surgery data, medical history, electrocardiogram (ECG) and laboratory test results, were collected from the patients. Perioperative cardiac events were taken as ending events including unstable angina pectoris (UAP), cardiac death, acute myocardial infarction (AMI), congestive heart failure (CHF), malignant arrhythmia and non-fatal cardiac arrest during or after surgery (only in hospital). Results Compared with non-cardiac event group, the percentages of cases with CHD history, cardiac functional capacity≤4METs, ST-segment depression≥0.05 mV and transfusion of concentrated red blood cells (CRBC) during surgery increased in cardiac event group (all P<0.05). The results of multi-factor Logistic regression analysis showed that CHD history (OR=4.672, 95%CI: 1.648~12.990), cardiac functional capacity≤4METs (OR=2.727, 95%CI: 1.079~6.892), ST-segment depression≥0.05 mV (OR=4.642, 95%CI: 1.865~11.557) and transfusion of CRBC during surgery (OR=7.102, 95%CI: 2.791~18.073) were independent risk factors of perioperative cardiac events during non-cardiac surgery. The area under receiver operating characteristic curve (ROC) of above 4 risk factors was, respectively, 0.757, 0.693, 0.656 and 0.672. Conclusion The independent risk factors of perioperative cardiac events during non-cardiac surgery are CHD history, cardiac functional capacity≤4METs, ST-segment depression≥0.05 mV and transfusion of CRBC during surgery in hypertensive patients undergone non-cardiac surgery. CHD history is more accurate in predicting perioperative cardiac events occurrence.
Keywords：HypertensionPerioperative periodCardiac eventsRisk factors
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 360-362 )