Application of guard wire technique in interventional treatment of chronic total occlusion of coronary artery

Li Bingqiang; Wang Yaohui; Zong Xuemei; Li Ying

doi:10.3969/j.issn.1674-4055.2018.02.24

Abstract：Objective To observe the application effect of guard wire technique during percutaneous coronary intervention (PCI) in patients with chronic total occlusion (CTO) of coronary artery, Methods The patients with CTO of coronary artery (n=70, male 46, female 24, aged from 41 to 75 and average age=64.9±3.9) were chosen from the Department of Cardiology of the First People's Hospital of Pingdingshan City from June 2015 to Apr. 2017, and then they were randomly divided into guard wire group and routine group (each n=35). The routine group was given PCI according to routine procedure, and guard wire group was given PCI by using guard wire technique. The X-ray exposure time, success rate of PCI, dose of contrast agent, PCI-related complications, and major adverse cardiovascular events (MACE) and secondary end-point events after PCI for 30 d were recorded in 2 groups. The indexes of left ventricular ejection fraction (LVEF), 6-minute walk distance (6MWD), brain natriuretic peptide (BNP) and serum creatinine (SCr) were detected before and 1 month after PCI. Results The X-ray exposure time was shorter [(47.0±10.0) min vs. (40.0±5.1) min], success rate of PCI increased (71.4% vs. 91.4%), and dose of contrast agent decreased [(202.9±13.8) mL vs. (193.0±8.1) mL] in guard wire group compared with routine group (all P<0.05). The PCI-related complications were decreased in guard wire group compared with routine group (40.0% vs. 8.6%, P<0.05). The indexes of LVEF, 6MWD, BNP and SCr were all improved significantly in 2 groups after PCI, and they were improved more significantly in guard wire group (all P<0.05). Conclusion Compared with routine technique, guard wire technique can improve the success rate of PCI and heart function, and reduce incidence of PCI-related complications in patients with CTO of coronary artery.