Analysis on application of cardiac magnetic resonance T1 Mapping and ECV techniques of dilated cardiomyopathy myocardial fibrosis evaluation
Li Yan
Huang Lingbo
Fu Bing
Yang Zhi
Zhao Zhiyong
Wang Bo
Abstract：Objective To explore the application of cardiac magnetic resonance T1 Mapping and ECV techniques of dilated cardiomyopathy myocardial (DCM) fibrosis evaluation. Methods 63 patients with DCM were selected as DCM group, and 52 healthy subjects were selected as the control group. All the subjects were given T1Mapping imaging and delayed gadolinium enhanced scan. Left ventricular ejection fraction (LVEF), left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVEDI), and stroke volume were compared between the two groups. According to appearance of delayed enhancement (LGE), subjects were divided into LGE group and non-LGE group. T1 value before enhancement, T1 and ECV value at 5min, 15min, 30min after enhancement were compared, and the receivers operating characteristic curve (ROC) was constructed to calculate area under curve (AUC) of TI before enhancement, ΔTI, ECV, and TI. Diagnostic efficacy of ΔTI, ECV were compared. Results Left ventricular mass index, LVEDV and LVEDI in DCM group were higher than those in the control group, and LVEF and stroke volume were lower than those in the control group, with statistically significant difference (P<0.05). There was no significant difference in heart rate between the two groups (P>0.05). T1 value before enhancement, T1 and ECV value at 5min, 15min, 30min after enhancement in DCM group were higher than those in the control group, with statistically significant difference (P<0.05). In DCM group, there were 43 cases of LGE and 19 cases of non-LGE. T1 value before enhancement, T1 and ECV value at 5min, 15min, 30min after enhancement in LGE group were all higher than those in non-LGE group, with statistically significant difference (P<0.05). AUC value of ECV was higher than that of ΔTI and T1 before enhancement. There was statistically significant difference in sensitivity and accuracy of T1 before enhancement, ΔTI, ECV (P<0.05). The sensitivity and accuracy of ECV were higher than those T1 before enhancement, with statistically significant difference (P<0.05),and there was no significant difference in sensitivity and accuracy of ΔTI, ECV (P>0.05).Conclusion It has good application value of cardiac magnetic resonance T1 Mapping and ECV echniques in evaluation of dilated cardiomyopathy myocardial fibrosis.
Keywords：Cardiac magnetic resonanceT1 MappingExtracellular volumeDilated cardiomyopathyMyocardial fibrosis
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 185-189 )