Effects of reshuvastatin on inflammatory factors and hemodynamics in patients with acute myocardial infarction after PCI therapy
Xie Jing
Min Qing
Abstract：Objective To explore the effect of resuvastatin on inflammatory factors and hemodynamics in patients with acute myocardial infarction after PCI. Methods 148 patients with acute myocardial infarction enrolled from August 2014 to August 2016 were randomly divided into control group (75 patients) and observation group (73 patients). The control group was given routine medication, the observation group was treated with resuvastatin on the basis of the control group. The changes of TG, TC, LDL-C, HDL-C, IL-6, TNF-α, hs-CRP, FIB, ESR, PV, NBL and NBH were detected before and after treatment. Result The levels of TG, TC, LDL-C and HDL-C before and after treatment in both groups were significantly improved, the difference was statistically significant (all P<0.05). Compared with those before treatment, the levels of IL-6, TNF-α and hs-CRP in both groups decreased after treatment, the difference was statistically significant (all P<0.05). Compared with those before treatment, the FIB, ESR, PV, NBL and NBH in both groups decreased after treatment, and were more decreased in the observation group than those in the control group, the difference was statistically significant (all P<0.05). Conclusion Resuvastatin can significantly improve the serum lipid level of patients with acute myocardial infarction after PCI treatment, while inhibiting serum inflammatory factor level and hemodynamic indexes.
Keywords：Acute myocardial infarctionResuvastatinPCIInflammatory factorsHemodynamics
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 82-84 )