Relationship between atrial fibrillation with erythrocyte distribution width, platelet distribution width and high sensitivity C-reactive protein
Cheng Xiaobing
Luo Juanjuan
Chen Yan
Pan Wenbo
Zhong Wansheng
Chen Dong
Liu Shenghao
Ding Ruyue
Sheng Chunmei
Liang Youfeng
Fan Zongcheng
Chen Qingli
Abstract：Objective To investigate the changes of High-sensitivity C-reactive protein (hs-CRP), Red blood cell distribution width (RDW) and Platelet distribution width (PDW) in patients with atrial fibrillation (AF) and their relationships with atrial fibrillation. Method A total of 60 AF patients were selected as AF group and 60 inpatients with sinus rhythm were selected as control group from Dec. 2015 to Sep. 2016. RDW, PDW were measured using automatic blood cell analyzer, hs-CRP was measured by ELISA, left atrium diameter (LAD), left interior diameter (LVD), interventricular septum (IVS), left ventricular posterior wall thickness (LVPW), left ventricular ejection fraction (LVEF) were measured by doppler echocardiography. There was no significant difference in sex ratio, age, the proportion of combined disease, red blood cell count and hemoglobin between the two groups (all P>0.05). The RDW, PDW, hs-CRP and LAD in atrial fibrillation group were significantly higher than those in control group (all P<0.05). Result of multivariate Logistic regression analysis showed that there were significant differences in the incidence of RDAD (OR=1.070, 95%CI: 1.015~1.121), PDW (OR=1.050, 95%CI: 1.019~1.082), LAD(OR=1.064, 95%CI: 1.021~1.098) is an independent risk factor for atrial fibrillation. Conclusion hs-CRP, RDW and PDW are elevated in patients with AF, and are risk factors for the onset of atrial fibrillation.
Keywords：Atrial fibrillationRed blood cell distribution widthHigh-sensitivity c-reactive proteinLeft atrium diameterPlatelet distribution width
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 43-45 )