Influence of borehole drainage guided by neuronavigation system on morphological function of corticospinal tract and severity of neurological impairment in patients with hypertensive intracerebral hemorrhage
Zhang Haiquan
Wang Zhiyong
Ao Xiangsheng
Liu Handong
Abstract：Objective To investigate the influence of borehole drainage guided by neuronavigation system on morphological function of corticospinal tract (CST) and severity of neurological impairment in patients with hypertensive intracerebral hemorrhage (HIH).Methods HIH patients (n=56) were chosen from the Central Hospital of Xiangyang City of Hubei Province from Jan. 2015 to Jan. 2016, and then randomly divided into control group treated with conservative therapy and observation group treated with borehole drainage guided by neuronavigation system (eachn=28). The ratio of values of ipsilateral/contralateral fractional anisotropy (FA) was examined before and after HIH onset for 3 months. The difference between grades 1-3 CST impairment and grade 4 CST impairment was compared, and improvement of neurological function was reviewed based on National Institute of Health Stroke Scale (NIHSS).Results The difference in baseline material including sex, age, bleeding position and CST impairment had no statistical significance between 2 groups (P>0.05). The difference in FA value had no significance between 2 groups before HIH onset (P>0.05). FA value was significantly higher in 2 groups after HIH onset for 3 months than before (P<0.05). FA value was higher in patients with grades 1-3 CST impairment in observation group than that in control group (P<0.05). The difference in FA value had no statistical significance in patients with grade 4 CST impairment between 2 groups after HIH onset for 3 months (P>0.05). The difference in NIHSS score had no statistical significance between 2 groups before HIH onset (P>0.05). NIHSS score was significantly lower in 2 groups after HIH onset for 3 months than before (P<0.05). NIHSS score was significantly lower in observation group than that in control group after HIH onset for 3 months (P<0.05).Conclusion The curative effect of borehole drainage guided by neuronavigation system has more advantages than conservative therapy in treatment of HIH.
Keywords：Hypertensive intracerebral hemorrhageCorticospinal tractPrognosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1501-1503,1506 )