Influence of early fractionated percutaneous coronary intervention for intervening non-infarct related artery on prognosis in patients with ST-segment elevation myocardial infarction
Huang Li
Wu Xiaopeng
Wang Xuanqi
Abstract：Objective To investigate the influence of early fractionated percutaneous coronary intervention (PCI) for intervening non-infarct related artery (Non-IRA) on prognosis in patients with acute ST-segment elevation myocardial infarction (STEMI).Methods STEMI patients (n=120) with multi-vessel lesions were chosen from the Department of Cardiovasology of the Fourth People's Hospital of Shaanxi Province from Jan. 2015 to Dec. 2016, and divided randomly into early fractionated PCI group (intervening non-IRA after successfully opening IRA by emergency PCI for 3-7 d) and rehospitalized PCI group. The baseline data, lesion features, and incidence of complications during hospitalization and in-hospital major adverse cardiovascular events (MACE) were compared between 2 groups. All patients were followed up for 6 months, and times of angina pectoris attack, heart function improvement and incidence of MACE were compared between 2 groups.Results The length of stay in hospital [(7.5±1.5) dvs. (11.5±2.3) d,P=0.02] and hospitalization expenses [(7658±30242) yuanvs. (79864±24980) yuan,P=0.04] were lower in early fractionated PCI group than those in rehospitalized PCI group. The incidence of complications during hospitalization [11 (18.3％)vs. 5 (8.3％),P=0.11] and MACE [4 (6.7％)vs. 2 (3.3％),P=0.68] was not increased in early fractionated PCI group. During 6-month follow-up period, the relief of angina pectoris [(1.8±0.5)vs. (3.1±0.6),P=0.04] and heart function improvement [(57.7±3.3)vs. (52.0±5.2),P=0.03] were superior in early fractionated PCI group to those in rehospitalized PCI group, and difference in incidence of MACE [(17.2％)vs. (10.5％),P=0.30] had no statistical significance between 2 groups.Conclusion The early fractionated PCI for intervening Non-IRA is safe and feasible. The length of stay and expenses in hospital are reduced, and incidence of complications during hospitalization and MACE were not increased. The prognosis was not worse in patients with early fractionated PCI than that in patients with rehospitalized PCI.
Keywords：Acute ST-segment elevation myocardial infarctionNon-infarct related arteryEarly fractionated percutaneous coronary intervention
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1478-1481 )