Relationship between eosinophil and slow coronary flow
Wang Jun
Chen Hao
Li Shijing
Jing Lixing
Pan Liming
Liu Jingjing
Zhang Anning
Hu Xinke
Feng Jing
Liu Xiaohua
Zou Aichun
Abstract：Objective To discuss the relationship between count of eosinophil and slow coronary flow (SCF). Methods The medical data from patients (n=494, male 163 and female 331) received coronary angiography (CAG) due to chest pain were retrospectively analyzed in the Department of Cardiology of Hospital of Beijing Mentougou District from Jan. 2013 to Dec. 2016. SCF patients with normal or almost normal CAG were chosen into case group (n=62) and those with normal coronary flow were chosen into control group (n=432). The baseline data, and results of blood biochemical examinations and blood routine examinations were all obtained from inpatient database.Results The count of eosinophil was significantly higher in SCF group than that in control group [(0.19 ±0.05)×109/Lvs. (0.11±0.04)×109/L,P<0.05]. The results of single-factor regression analysis showed that count of eosinophil was the risk factor of SCF (OR=5.376, 95％CI: 3.660～7.897,P<0.001). The results of multi-factor regression analysis showed that count of eosinophil (OR=7.567, 95％CI: 4.634～12.350,P<0.001) and fasting plasma glucose (OR=1.266, 95％CI: 1.087～1.474,P=0.002) were the risk factor of SCF. The count of eosinophil was positively correlated to coronary flow velocity (r=0.370,P<0.001) in SCF patients. The sensitivity of count of eosinophil was 96.8％, specificity was 64.8％ and AUC of ROC was 0.879 (95％CI: 0.843～0.916) in diagnosis of SCF.Conclusion The count of eosinophil is related to SCF, and increase of eosinophil may be valuable to the prediction of SCF.
Keywords：EosinophilSlow coronary flowCoronary angiography
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1464-1467 )