Predictive value of modified shock index and level of plasma lactic acid to short-term prognosis in patients with non-ST-segment elevation myocardial infarction
Zhao Chunsheng
Wang Yanfei
Sun Haiyan
Zhao Chunmei
Liang Hao
Li Junxia
Abstract：Objective To study the predictive value of modified shock index (MSI) and level of plasma lactic acid (LA) to short-term prognosis in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Methods NSTEMI patients (n=312) were chosen from the Department of Emergency in the Affiliated Hospital of Chengde Medical College from Jan. 2014 to Jan. 2017, and all patients were divided, according to MSI and LA level, into MSI≥1.2 group and MSI<1.2 group, and LA≥2 mmol/L group and LA<2 mmol/L group. The general data of the patients was recorded, short-term prognosis was reviewed and hospital mortality was observed, and predictive value of all indexes to short-term prognosis was analyzed by using area under curve (AUC) of receiver operating characteristic curve (ROC).Results The difference in systolic blood pressure, diastolic blood pressure, heart rate, left ventricular ejection fraction (LVEF) and grades Ⅲ and Ⅳ of Killip grading had statistical significance between MSI≥1.2 group and MSI<1 group (P<0.05). The difference in LVEF, cardiac troponin I (cTnI) and grades Ⅲand Ⅳ of Killip grading had statistical significance between LA≥2 mmol/L group and LA<2 mmol/L group (P<0.05). The incidence of fatal arrhythmias and cardiogenic shock and all-cause mortality were significantly higher in MSI≥1.2 group than those in MSI<1.2 group (P<0.05). The incidence of fatal arrhythmias and cardiogenic shock and all-cause mortality were significantly higher in LA≥2 mmol/L group than those in LA<2 mmol/L group (P<0.05). The hospital mortality was 18.59％. AUC of MSI was 0.794 and AUC of LA was 0.822, which had statistical significance in prediction of short-term prognosis in NSTEM patients.Conclusion MSI and LA all have some predictive value to short-term prognosis in NSTEM patients, and LA has higher predictive value.
Keywords：Modified shock indexLactic acidNon-ST-segment elevation myocardial infarctionPrognosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1455-1457,1463 )