Safety and long-term curative effect of percutaneous coronary intervention in treatment of severe coronary artery disease
Chen Zongning
Zhao Yuan
Zhuang Li
Abstract：Objective To investigate the safety and long-term curative effect of percutaneous coronary intervention (PCI) in treatment of severe coronary artery disease (CHD).Methods The patients with severe CHD (n=75, male 42, female 33, aged from 43 to 78 and average age=56.82±7.27) were chosen from the People's Hospital of Lijiang City of Yunnan Province from Jan. 2014 to Dec. 2016. All patients were randomly divided into sirolimus-eluting stent group (SES group,n=54) and bare metal stent group (BMS group,n=21). The patients were followed up for 12-27 months, and the incidence of in-stent restenosis and target lesion revascularization rate (TLR) were compared between 2 groups. The incidence of major adverse cardiovascular events (MACE), including cardiovascular death, myocardial infarction, heart failure and stroke, was compared between 2 groups.Results There were 86 lesions and 107 successfully implanted stents in 75 patients. There were 72 stents implanted with average diameter of (3.01±0.32) mm and average length of (23.10±4.32) mm in SES group, and 35 stents implanted with average diameter of (3.03±0.30) mm and average length of (22.43±4.26) mm in BMS group (all P>0.05). There were 4 cases of MACE (7.4％) in SES group and 6 (28.6％) in BMS group (P<0.05). The results of follow-up for 12-27 months showed that the incidence of in-stent restenosis was 47.6％ in BMS group and 3.7％ in SES group (P<0.05). TLR was 33.3％ in BMS group and 1.9％ in SES group (P<0.05).Conclusion The long-term curative effect and safety of SES are better than those of BMS in treatment of severe CHD with PCI.
Keywords：Sirolimus-eluting stentBare metal stentSevere coronary artery diseaseSafetyLong-term curative effect
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1452-1454 )