Correlation among urea albumin creatinine ratio, cystatin C and SYNTAX scores in patients with coronary heart disease
Cao Yukang
Yang Bo
Sun Zhijun
Zhang Jian
Abstract：Objective To analyze the correlation among urea albumin creatinine ratio (UACR), cystatin C (Cys C) and SYNTAX scores of coronary artery lesions in patients with coronary heart disease (CHD).Methods The data was retrospectively analyzed from CHD patients (n=184, male 122, female 62, aged from 39 to 84 and average age=56.5±10.8) in the Chinese PLA General Hospital from Oct. 2016 to Mar. 2017. All patients were given examination of coronary angiography (CAG) after hospitalization, and were scored based on SYNTAX scoring system. The patients were divided, according to SYNTAX scores, into low-score group (0-22,n=140), mid-score group (23-32,n=34) and high-score group (≥33,n=10). The level of UACR in morning urine and Cys-C level in morning fasting venous blood were detected in patients after hospitalization.Results The level of UACR was significantly higher in mid-score group and high-score group than that in low-score group, and Cys-C level was significantly higher in high-score group than that in low-score group (allP<0.05). SYNTAX scores was positively correlated to Cys-C (r=0.12) and UACR (r=0.31,P<0.05). The analysis of multiple linear regression showed that Cys-C (β=0.212,P=0.031) and UACR (β=0.212,P<0.001) were influence factors on SYNTAX scores. Conclusion There is a positive correlation among UACR, Cys C and SYNTAX scores in CHD patients, and UACR and Cys C are influence factors on SYNTAX scores.
Keywords：Coronary heart diseaseUrea albumin creatinine ratioCystatin CSeverity of coronary artery lesionsSYNTAX scores
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1439-1441 )