Correlation between ABO blood group and onset time of deep sternal wound infection after cardiac surgical procedure
Ma Jiagui
Wang Wenzhang
An Jianxiong
Zhang Xinghua
Wu Weiwei
Cui Wen
Wu Xumin
Abstract:Objective To study the correlation between ABO blood group and onset time of deep sternal wound infection (DSWI) after cardiac surgical procedure. Methods The clinical materials from DSWI patients (n=84), chosen from Aviation General Hospital of China Medical University from Jan. 2012 to Dec. 2014, were retrospectively analyzed. All patients were divided, according to disease onset time, into early onset group (onset time<14 d) and late onset group (onset time≥14 d). The data was collected from the patients, and the correlation between ABO blood group and onset time of DSWI was analyzed by using multiple-Logistic regression analysis model. Results The age, male proportion, smoking rate and percentage of coronary artery bypass grafting (CABG) were higher in early onset group than those in late onset group (all P<0.05). The percentage of patients with O-type blood (46.7%) was higher in early onset group than that in late onset group (27.8%), but the difference has no statistical significance (P=0.081). After correcting age, sex, smoking, hypertension, diabetes, hyperlipidemia and initial surgery types, the results of multiple Logistic regression analysis showed that, when O-type blood was taken as reference type, the risk of late onset DSWI was higher by 8 times to 12 times in patients with A-type blood (OR=8.398, 95%CI: 1.521-46.370, P=0.015) and those with B-type blood (OR=11.913, 95%CI: 1.944-73.007, P=0.007) than that in patients with O-type blood. Conclusion The patients with A-type blood or B-type blood have higher risk of late onset DSWI when they receive cardiac surgical procedure.
Keywords:Cardiac surgerySurgical wound infectionABO blood groupOnset time
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 1365-1367,1371 )
