Correlation among serum high-sensitivity C-reactive protein, cardiac troponin I and early recurrence of paroxysmal atrial fibrillation after radiofrequency ablation
Yang Shaohui
Dong Pingshuan
Lai Lihong
Wang Honglei
Abstract：Objective To investigate the relationship among serum high-sensitivity C-reactive protein (hs-CRP), cardiac troponin I (cTnI) and early recurrence of paroxysmal atrial fibrillation (PAF) after radiofrequency ablation (RFA).Methods PAF patients (n=60) were chosen from the Department of Cardiology of the First Affiliated Hospital of Henan University of Science and Technology from Oct. 2014 to Sept. 2016. All patients were received for the first time circumferential pulmonary vein isolation guided by 3-D mapping system (EnSite-NAVX noncontact mapping). The patients were divided into success group (n=44) and recurrence group (n=16) according to PAF recurrence situation (observation indexes including patients'autonomic symptoms, 12-lead electrocardiogram and 24-h ambulatory electrocardiograph results) within 3 months after RFA. The vein blood samples were collected for detecting levels of hs-CRP and cTnI before the operation and on the 1st d, 2nd d and 3rd d after the operation.Results The peak levels of hs-CRP and cTnI increased significantly in 2 groups after the operation (P<0.05). The difference in changes of cTnI and hs-CRP had no statistical significance in 2 groups before the operation (P>0.05). The peak level of hs-CRP after the operation, and the maximum difference of hs-CRP level before and after the operation increased significantly in recurrence group compared with success group (P<0.05). The peak level of cTnI after the operation, and the maximum difference of cTnI level before and after the operation had no statistical difference between 2 groups (P>0.05).Conclusion The changes of hs-CRP level is related to early recurrence of PAF after RFA, while cTnI level is not correlated to that.
Keywords：Paroxysmal atrial fibrillationRadiofrequency ablationHigh-sensitivity C-reactive proteinCardiac troponin I
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1236-1239 )