Ultrasound study of correlation between epicardial adipose tissue thickness and coronary artery disease

Huang Xiaoyun; Guo Weihong; Wang Xuewei; Niu Xiaoxian; Tong Feng

doi:10.3969/j.issn.1674-4055.2017.09.23

Abstract：Objective To investigate correlation between epicardial adipose tissue thickness and coronary artery disease by ultrasound imaging. Methods 98 hospitalized patients from January 2013 to December 2016 underwent coronary artery ultrasound examination for unclear causes of angina, myocardial infarction and chest pain were selected. the clinical data of patients were collected. Epicardial adipose tissue thickness were measured by echocardiographic. The Gensini score was used to evaluate the severity of coronary artery lesions in patients with coronary heart disease (CHD) patients. Patients were divided into CHD group and non-CHD group, CHD group was divided into mild group, moderate group and severe group according to severity of CHD. Results There were no significant differences between CHD group and non- CHD group with respect of sex, age, systolic blood pressure, fasting blood glucose, total cholesterol, three triglyceride, high density lipoprotein and fasting insulin (P>0.05). body mass index, waist circumference, coronary heart disease patients with diastolic blood pressure, low density lipoprotein and epicardial adipose tissue (EAT) thickness were significantly higher in CHD group (P<0.05). The EAT of CHD group was thicker than that of non-CHD group, and the greater the degree of coronary artery lesion, the greater the EAT thickness, the difference was statistically significant (P<0.05). Result of Spearson correlation analysis showed that EAT thickness and low density lipoprotein, diastolic blood pressure, body mass, waist circumference was positively correlated. Result of logistic regression analysis showed that EAT thickness was independent risk factor of coronary artery disease (P<0.05). Conclusion Epicardial adipose tissue thickness is positively correlated with the severity of coronary artery disease. It is an independent risk factor for coronary artery disease. Measurement of epicardial adipose tissue thickness is simple, noninvasive and worthy of clinical promotion.