Correlation between monocyte-high-density lipoprotein ratio and major adverse cardiovascular events in patients with STEMI undergone emergency PCI
Yu Yongfu
Wang Lanfeng
Abstract：Objective To discuss the relationship between monocyte-high-density lipoprotein ratio (MHR) and in-hospital major adverse cardiovascular events (MACE) in patients with ST-segment elevation myocardial infarction (STEMI) undergone emergency percutaneous coronary intervention (PCI).Methods STEMI patients undergone emergency PCI (n=286, male 193, female 93 and aged from 40 to 80) were chosen from the CCU of the First Affiliated Hospital of Harbin Medical University from Oct. 2015 to June 2016. All patients were divided, according to onset of MACAE within one week after hospitalization, into MACE group (n=131) and non-MACE group (n=155). The levels of total cholesterol (TC), triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), C-reactive protein (CRP), creatine kinase-MB isoenzyme (CK-MB), MHR and left ventricular ejection fraction (LVEF) were detected when patients were hospitalized.Results LVEF decreased, and CK-MB and MHR increased in MACE group compared with non-MACE group (allP<0.05). The results of multi-factor Logistic regression analysis showed that CRP (OR=1.009, 95％CI: 1.001～1.016), LVEF (OR=0.934, 95％CI: 0.905～0.963) and CK-MB (OR=1.003, 95％CI: 1.001～1.004) were influence factors of in-hospital MACE in STEMI patients. The increase of MHR was a risk factor of in-hospital MACE in STEMI patients. Conclusion MHR is correlated to MACE in STEMI patients undergone PCI, and the more the MHR is, the higher the risk of MACE is.
Keywords：Monocyte-high-density lipoprotein ratioST-segment elevation myocardial infarctionMajor adverse cardiovascular events
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 963-965 )