Curative effect of anti-anxiety therapy in elderly patients with hypertension in flood-ravaged area
Feng Qiang
Zhang Liangqing
Zhang Nannan
Chen Juan
Li Zhiying
Abstract：Objective To investigate the influence of anti-anxiety therapy on blood pressure (BP) and relevant indexes in elderly patients with hypertension in flood-ravaged area.Methods The elderly patients with hypertension (n=276, male 193, female 83, aged from 61 to 79 and average age=69.45±0.37) were chosen from the Central Hospital of Handan City during the period of fighting the flood and providing relief from July 2016 to Sept. 2016. All patients were divided, according to random digital table, into treatment group and control group (eachn=138). The treatment group was given estazolam and psychological dredging treatment on the base of routine antihypertensive drug (Nifedipine Sustained-release Tablets), and control group was only given routine antihypertensive drug. The indexes of 24-h mean systolic blood pressure (SBP), 24-h mean diastolic blood pressure (DBP), Hamilton Anxiety Scale (HAMA), morning blood pressure surge (MBPS), 24-h standard systolic deviation (SSD), pulse pressure index (PPI), ambulatory arterial stiffness index (AASI), central aortic systolic blood pressure (CSBP) and pulse wave velocity (PWV) were detected before and 8 weeks after treatment.Results The levels of 24-h SBP and 24-h DBP all decreased in 2 groups after treatment (all P<0.05). The patients had anxiety in 2 groups before treatment, and scores of HAMA decreased in treatment group after treatment (P<0.05). After treatment, the levels of 24-h SBP, 24-h DBP and scores of HAMA all decreased in treatment group compared with control group (all P<0.05). After treatment for 8 weeks, the levels of MBPS, 24-h SSD and PPI decreased in 2 groups (all P<0.05), and the decreases were more significant in treatment group (all P<0.05).Conclusion Flood disaster and rebuilding after the disaster will cause anxiety in elderly patients with hypertension. At the same time of routine antihypertensive treatment, anti-anxiety therapy and psychological dredging treatment can effectively improve BP control efficacy.
Keywords：Flood disasterSenile hypertensionAnxietyVessel stiffnessBlood pressure variability
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 960-962,965 )