Effect of salvianolate on unstable angina
Xue Li
Ou Shulin
Bao Honggang
Xu Yong
Abstract:Objective To investigate the effect of salvianolate injection on unstable angina.Methods 280 patients with unstable angina were divided into control group and experimental group randomly. All enrolled patients were treated with ordinary anti-angina medicines which were consisted of β receptor blocker, aspirin, lower molecular weight heparin subcutaneous injection and intravenous nitroglycerin. The patients in experimental group were treated with salvianolate injection for 15 days in addition to receiving ordinary anti-angina medicines. The angina attack and ECG and inflammatory factors were compared between two groups.Result The patients in experimental group suffered less angina attacks and the duration was shorter than patients in control group. The myocardial ischemia on electrocardiography (ECG) of experimental group was significantly improved (P<0.05). The inflammatory factors hs-CRP and TNF-α in experimental group were higher than those in control group. Conclusion The combination of ordinary treatments and salvianolate injection has remarkable curative effect on unstable angina.
Keywords:SalvianolateCoronary heart diseaseAnginaInflammatory factorsCurative effect
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 851-853 )