Application value of ultrasonic detection of epicardial adipose tissue combined with ischemia modified albumin in diagnosis of coronary heart disease
XIAO Jian-dong
ZHANG Jun-ling
LU Yu-li
ZHANG Shu-zhi
MA Xing
ZHENG Qun
Abstract：Objective To discuss the value of cardiac ultrasonic detection of epicardial adipose tissue (EAT) combined with ischemia modified albumin (IMA) in diagnosis of coronary heart disease (CHD).Methods CHD patients (n=150) were chosen into case group from the Harrison International Peace Hospital in Hengshui City from May 2014 to Dec. 2015, and then divided, according to the results of Judkins coronary angiography, into 1-vessel lesion group, 2-vessel lesion group and multi-vessel lesion group (eachn=50). At the same time the health controls (n=50) had physical examinations were chosen into control group. All groups were given echocardiogram for detecting the thickness of EAT, and concentration of serum IMA was detected by using albumin cobalt binding test (ACB test).Results The thickness of EAT and concentration of serum IMA were significantly higher in 1-vessel lesion group, 2-vessel lesion group and multi-vessel lesion group than those in control group (P<0.01). When receiver operating characteristic curve (ROC) showed that thickness of EAT was 6.03 mm, the sensitivity was 52.16% and specificity was 86.3%. When concentration of serum IMA was 72U/L, the sensitivity was 76% and specificity was 72.2%. When thickness of EAT combined with concentration of serum for diagnosis in serial tests, the sensitivity was 39.26% and specificity was 95.76%, and when the test in parallel, the sensitivity was 87.2% and specificity was 64.31%.Conclusion The ultrasonic detection of EAT thickness and serum IMA concentration has some reference value in the diagnosis of CHD, and the combination of them can significantly increase the correct diagnosis rate and accuracy rate.
Keywords：Coronary heart diseaseCardiac ultrasonographyEpicardial adipose tissueIschemia modified albuminCombined diagnosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 687-689 )